Nobilis® ND Broiler

A vaccine intended for the active immunisation of day-old broiler chickens against Newcastle Disease.

For Animal Use Only
REG. NO. G2469 (Act 36/1947)
NAMIBIA REG. NO. V98/24.3/676 NS0

NOBILIS® ND BROILER is an inactivated vaccine intended for the active immunisation of day-old broiler chicks against Newcastle Disease.


  • Store in the dark between 2 ºC and 8 ºC. Do not freeze.
  • Avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
  • Protect from direct sunlight.


Each 0,1 mℓ dose of NOBILIS® ND BROILER contains ≥ 20 PD50 units of inactivated Newcastle Disease virus (the Newcastle Disease virus antigen induces ≥ 4 log2 HI units per 1/50 dose).  The virus is inactivated with formalin and suspended in the aqueous phase of a water-in-oil emulsion. 


  • Do not freeze or heat.
  • Destroy any unused vaccine as well as all vaccine containers in accordance with local waste disposal regulations, after use.
  • Do not store partially used bottles for future use and use the entire contents once the vaccine has been opened.
  • After opening, the contents of the bottle should be used within 3 hours.
  • Opened bottles not used should be destroyed.
  • Do not market chickens for slaughter purposes for at least 6 weeks after vaccination.
  • Ensure that chickens marketed do not have swellings at the vaccination site, as this may result in the condemnation of the chickens.
  • Do not mix the vaccine with other vaccines, except when administered simultaneously with live Newcastle Disease vaccines.
  • Vaccination of chickens in production may lead to a slight drop in egg production.
  • Accidental self-injection may lead to a severe local allergic reaction.  Consult a physician informing him/her that the vaccine contains a mineral oil.
  • Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons.  If this is suspected, seek veterinary advice and notify the registration holder. 


  • Vaccinate healthy chickens only.
  • Observe aseptic precautions. Ensure that all vaccination equipment (needles, syringes, etc.) are clean and sterile prior to use.
  • Ensure that all equipment is kept clean and sterile during vaccination.
  • Avoid intravenous injection.
  • It is essential to adhere to the vaccination programme to maintain a satisfactory immune response.
  • It is good vaccination practice to avoid contact with the eyes, hands and clothing when handling the vaccine.

Directions For Use 

Recommended Vaccination Programme
NOBILIS® ND BROILER is administered by injection to day-old chickens, in combination with a live Newcastle Disease vaccine (eg. NOBILIS® ND CLONE 30), administered according to the manufacturer’s instructions.  The chickens vaccinated in this way will be protected against Newcastle Disease for up to 8 to 9 weeks of age.

Dosage and Administration

  • Inject 0,1 mℓ per broiler chicken intramuscularly into the thigh, or subcutaneously into the back of the neck.
  • Allow the vaccine to gradually reach room temperature (20 ºC to 25 ºC) prior to use.
  • Shake well before use and at regular intervals during the vaccination process.
  • Remove the aluminium overseal and the vaccine is ready for use.
  • Inject all the chickens in the flock.

Vaccination Reactions

  • In healthy chickens no clinical reaction to the vaccination will be observed.  For some weeks after vaccination a slight swelling may be felt at the site of injection.  This does not constitute permanent damage of the tissue, provided the vaccination has been carried out aseptically.
  • No interactions have been found when administered simultaneously with live Newcastle Disease vaccines.

Bottles containing 500 mℓ, sufficient for 5 000 doses respectively, packed in outer cardboard cartons.

Intervet International B.V.
35 Wim de Körverstraat, Boxmeer
The Netherlands

Registration Holder
Intervet South Africa (Pty) Ltd.
20 Spartan Road
Spartan, 1619
Tel: +27 (0) 11 923 9300
Fax: +27 (0) 11 392 3158

Date of Publication of This Package Insert

July 2003