Product Details - NOBILIS® ILT

Poultry

Product Class

FOR ANIMAL USE ONLY

NOBILIS®ILT
Reg. No. G2450 (Act 36/1947)
Kenya Reg. No. 8080
Namibia Reg. No. V98/24.3/675 NS0

INDICATIONS
Nobilis® ILT is a live attenuated vaccine for the prevention and emergency vaccination of chickens against Infectious Laryngotracheitis via eye drop administration.

COMPOSITION
Each dose of Nobilis® ILT contains a freeze dried chicken embryo propagated culture of a modified strain of Infectious Laryngotracheitis virus.

CONTENTS
Each dose contains at least 2,5 log10 EID50 of live Infectious Laryngotracheitis virus Serva strain with stabilisers.

STORAGE

  • Store in the dark between 2 ºC and 8 ºC.
  • Do not freeze.
  • Avoid prolonged or repetitive exposure to high ambient temperatures.
  • Protect from exposure to direct sunlight.
  • Solvent: May be stored at room temperature (20 ºC to 25 ºC).

WARNINGS

  • Withdrawal period: Do not vaccinate within 21 days before slaughter.
  • It is advisable to vaccinate all the susceptible chickens on the farm at the same time. If this is not feasible, strict separation of vaccinated and unvaccinated chickens should be done to prevent the spread of the vaccine virus to the unvaccinated chickens.
  • Protect the reconstituted vaccine from direct sunlight.
  • Do not mix Nobilis® ILT with other vaccines.
  • Do not administer simultaneously with or within 14 days after vaccination with other live vaccines.
  • Use according to the number of doses as indicated on the label.
  • Vaccination may cause a slight transient conjunctivitis in some chickens.
  • All reconstituted vaccine should be used within 2 hours after reconstitution.
  • Do not store partially used containers for future use.
  • Destroy any unused, reconstituted vaccine, empty vaccine containers, needles etc. according to local waste disposal regulations after completion of the vaccination.
  • KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
  • Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

PRECAUTIONS

  • Vaccinate healthy chickens only.
  • Observe aseptic conditions. Ensure that all vaccination equipment (needles, syringes, etc.) are clean and sterile before use.
  • Ensure that all equipment is kept clean and sterile during use.
  • Each vial should be used immediately after opening.
  • Keep the bottle inverted, i.e. in a vertical position, to ensure the correct droplet size and to avoid loss of vaccine.
  • It is good vaccination practice to avoid contact with the eyes, hands and clothing when handling the vaccine.

DIRECTIONS FOR USE - USE ONLY AS DIRECTED
The vaccine is administered via eye drop administration.

PREPARATION OF THE VACCINE SOLUTION

  • Open the vaccine and diluent vials.
  • Connect them by using the plastic connector tube.
  • Shake the connected vials until the vaccine is dissolved.
  • Remove the small vial, transfer the liquid into plastic vial and affix the dropper.
  • On no account should the vaccine be exposed to direct sunlight.

DOSAGE AND ADMINISTRATION

  • Instill 1 drop into an eye of each chicken.
  • Allow the drop to spread across the surface of the eye. Do not release the chicken until a swallowing motion is noticed.
  • Keep the dropper bottle inverted, in a vertical position, to ensure correct droplet size and to avoid loss of vaccine.
  • Note: Once dissolved, the vaccine is very vulnerable. All the vaccine should be used within 2 hours of reconstitution.

VACCINATION PROGRAMMES
It is recommended to vaccinate susceptible chickens at the age of 4 to 6 weeks and to revaccinate at 14 to 16 weeks of age.
In emergency cases, the chickens may be vaccinated earlier, but should then always be revaccinated 1 month before the start of the laying period, also by eye drop administration.

Immunity
The vaccine has been prepared from a special strain, modified to allow eye drop administration from the first vaccination onwards. Vaccination by this method produces early immunity (4 to 5 days post vaccination) which will last for about 1 year if the chickens are vaccinated in accordance with the above programme.

PRESENTATION
Cardboard boxes containing 10 vials of 1 000 or 2 500 doses each.

REGISTRATION HOLDER
Intervet South Africa (Pty) Ltd.
20 Spartan Road
Spartan
1619, RSA
Tel: +27 (0) 11 923 9300
Fax: +27 (0) 11 392 3158
www.msd-animal-health.co.za

MANUFACTURER
Intervet International B.V.
35 Wim de Körverstraat
Boxmeer, The Netherlands

Zimbabwe Reg. No.: E95/80.23.10/9404
Pharmacological classification: 802310
Distribution category: VMGD

DATE OF PUBLICATION OF THE PACKAGE INSERT
January 1998