NOBILIS® RHINO CV
For the active immunisation of chickens to reduce infection with avian rhinotracheitis virus (avian pneumovirus) and to reduce clinical signs and effects of the disease caused by the virus.
FOR ANIMAL USE ONLY
NOBILIS® RHINO CV
Reg. No. G3278 (Act 36/1947)
For the active immunisation of chickens to reduce infection with avian rhinotracheitis virus (avian pneumovirus) and to reduce clinical signs and effects of the disease caused by the virus.
COMPOSITION
Each vial contains at least 101,5 TCID50 and maximally 103,7 TCID50 per dose of live attenuated avian rhinotracheitis virus (avian pneumovirus) strain TRT 11/94.
- Store at 2 °C to 8 °C.
- Do not freeze.
- Keep the container in the outer carton in order to protect from light.
- Withdrawal period: The product is not intended for use in hens in lay or breeding hens within 4 weeks before the onset of the laying period.
- Vaccinate healthy chickens only.
- Vaccination with Nobilis® Rhino CV may occasionally cause slight nasal discharge in some chickens.
- It is recommended that no other vaccines should be administered within 14 days before or after vaccination with Nobilis® Rhino CV.
- KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
- Although this vaccine has been extensively tested under a large variety of conditions failure thereof may ensue as a result of a wide range of reasons. If this is suspected seek veterinary advice and notify the registration holder.
- Do not mix with any other immunological veterinary medicinal product.
- If the oculonasal or spray method is used for the administration of the vaccine, ensure that there is no iron, chloride or disinfectants in the water.
- Dispose of all unused vaccine, empty containers and disposable equipment in accordance to local waste disposal regulations.
- It is good vaccination practice when handling the vaccine to avoid contact with the eyes, hands and clothing.
- After reconstitution the vaccine should be used within 2 hours of reconstitution and not be stored for future use.
DIRECTIONS FOR USE – USE ONLY AS DIRECTED
For oculonasal or spray administration.
Each chicken should receive 1 dose of vaccine.
- · General guideline
The vaccine can be administered to 1-day-old chicks and older chickens by coarse spray or by the oculonasal route of administration.
The optimum time and method of administration depend largely upon the local situation. Veterinary advice should be sought.
The vaccine is supplied as a freeze-dried pellet that should be dissolved in cool, clean water which if free of iron and chlorine.
Chlorine at levels as low as 1 ppm is known to have a detrimental effect on vaccine virus stability.
After mixing, the solution should be allowed to stand for 15 to 30 minutes before adding the vaccine.
When dissolving the vaccine: do not shake, but mix thoroughly with a clean stirrer, avoiding frothing.
Care must be taken to apply the vaccine promptly after reconstitution.
- · Oculonasal Administration
See general guideline above.
Dissolve the vaccine in clean, non-chlorinated water and administer by means of a standardised dropper.
The drop size of the dropper must equal one dose; therefore, the vaccine must be dissolved in an appropriate volume of water.
For instance, if the drop size of the dropper is 0,03 mℓ, the vaccine should be reconstituted at 1 000 doses per 30 mℓ.
- · Spray Method
See general guideline above.
Dissolve the vaccine in cool, clean, non-chlorinated water. The appropriate number of vials should be opened under the surface of the water.
Where the number of chickens is between the standard dosages, the next higher dosage should be used.
The volume of water for reconstitution should be sufficient to ensure an even distribution when sprayed onto the chickens. This will vary according to the age of the chickens being vaccinated and the management system, but 250 to 500 mℓ of water per 1 000 doses is suggested.
Apply the vaccine promptly after reconstitution.
The vaccine suspension should be spread evenly over the correct number of chickens, at a distance of 30 to 40 cm using a coarse spray, preferably when the chickens are sitting together in dim light. The spray apparatus should be free from sediments, corrosion and traces of disinfectants and should be used for vaccination purposes only.
The optimum time and method of administration depend largely upon the local situation. The advice of a veterinarian should be sought.
Cardboard box containing 10 x 10 mℓ vials, each vial containing 1 000, 2 500 or 5 000 doses of freeze-dried vaccine.
Intervet South Africa (Pty) Ltd.
20 Spartan Road, Spartan
1619, RSA
Tel: +27 (0) 11 923 9300
E-mail: msdahza@msd.com
www.msd-animal-health.co.za
MANUFACTURER
Intervet International B.V.
35 Wim de Koverstraat
Boxmeer, The Netherlands
DATE OF PUBLICATION OF THIS PACKAGE INSERT
23 October 2018