Nobilis® ND Clone 30

A live freeze-dried vaccine, indicated for the immunisation of fowls against Newcastle Disease (NCD).




Reg. No. G2466 (Act 36/1947)

Kenya Reg. No. 4641

Namibia Reg. No. V98/24.3/672 S0

Zimbabwe Reg. No. 94/80.23.10/9363

A live freeze-dried vaccine to prevent Newcastle Disease in chickens. It is administered by the coarse spray or eye drop method. 


  • Store in the dark between 2 ºC and 8 ºC. Do not freeze.
  • Avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
  • Protect from direct sunlight.


NOBILIS® ND CLONE 30 contains a live freeze-dried vaccine virus strain Clone 30. 


Each dose of vaccine contains at least 106 EID50 of the Newcastle Disease vaccine virus strain Clone 30. The vaccine pellet contains stabilisers and gentamycin.


  • Do not vaccinate within 21 days of slaughter.
  • Do not administer the vaccine simultaneously with or within 7 days after the vaccination with any other live vaccine.
  • It is advisable to vaccinate all the susceptible chickens on the farm at the same time.
  • If this is not feasible, strict separation of vaccinated and unvaccinated chickens should be done to prevent the spread of the vaccine virus to the unvaccinated chickens.
  • Destroy any unused, reconstituted vaccine, empty vaccine containers, needles, etc. for instance by burning after completion of the vaccination.
  • Do not store partially used vaccine containers for future use.
  • Protect the reconstituted vaccine from direct sunlight.
  • Do not mix the vaccine with other vaccines.
  • Use according to the number of doses as indicated on the label.
  • Wash and disinfect hands and equipment after vaccinating.
  • Keep out of reach of children and uninformed persons.
  • Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.


  • Vaccinate healthy chickens only.
  • If the spray method is used for the administration of the vaccine, ensure that there is no chlorine, iron or disinfectants in the water.
  • If the spray method is used ensure that the spray apparatus is free from sediments, corrosion and traces of disinfectants.
  • Each vial should be used immediately after opening.
  • It is good vaccination practice to avoid contact with the eyes, hands and clothing when handling the vaccine.

Directions for Use

Use only as directed.


The vaccine may be administered by coarse spray or eye drop installation. (For eye drop installation the Diluent Oculo-Nasal may be used).

A. Spray Method

The vaccine should be dissolved in cool, clean, non-chlorinated water which is free from iron and chlorine. The vials of freeze-dried vaccine should be opened under water. The spray apparatus should be free from sediments, corrosion and traces of disinfectants (preferably to be used for vaccination purposes only.)

The vaccine medicated water should be spread evenly over the correct number of chickens, at a distance of 30 – 40 cm, preferably when the chickends are sitting together in dim light.

Dissolve 1 000 doses per litre of water and set the nozzle to produce fine droplets falling like fine rain, (aerosol generators should be used only when this is known to be safe in chickens).

B. Eye Drop Application

Dissolve the vaccine in Diluent Oculo-Nasal may be used. Administer by means of a standardised dropper (usually 30 ml per 1 000 doses). One drop should be applied from a height of a few centimetres onto one eye. The eye drop should be allowed to spread across the surface of the eye.

The diluent contains a dye (patent blue) which allows an easy check on the correct vaccination. Do not release the chickens until a swallowing motion is noticed.

Vaccination Programme

The optimum time and method of administration depends largely upon the local situation. Therefore the advice of a veterinary surgeon should be sought. The vaccine is safe to use from day 1 of age onwards.

Immunity and Vaccination Reaction

Duration and intensity of the vaccination reaction and the establishment of a solid immunity are generally dependent on the health and condition of the chickens. Hygiene and management are also important in the post vaccination period.

An adequate immunity against Newcastle Disease will last for approximately 6 weeks. In areas where Newcastle Disease is endemic (high risk areas) a second vaccination with NOBILIS®ND CLONE 30 should be given within approximately 2 – 4 weeks after the first. Consult your Veterinarian. Emergency vaccination during the laying period may be accompanied by a transient drop in egg production.


Vials containing either 1 000, 2 500 or 5 000 doses.

Registration Holder

Intervet South Africa (Pty) Ltd.

20 Spartan Road,

Spartan, 1619


Tel: +27 (0) 11 923 9300

Fax: +27 (0) 11 392 3158