Product Details - LT-IVAX® ASL

 Reg. No. G3603 (Act 36 /1947)

Indications:
Modified live virus vaccine  for use in fowls 4 weeks of age or older, as an aid in the prevention of fowl laryngotracheitis through vaccination by the EYEDROP METHOD.

Storage Instructions:
Store between 2°C and 7°C. 

Composition:
LT-IVAX ASL vaccine contains a live virus of fowl tissue culture origin and contains gentamicin sulphate as preservative.

Contents:
Each dose contains 102.9 TCID50 fowl laryngotracheitis virus.

Warnings:

Do not vaccinate within 21 days before slaughter.
Vaccinate only healthy fowls.
Keep out of reach of children, uninformed persons and pets.
An eye reaction may be noticed if fowls are incubating coryza or other infectious organisms, or if there is excess ammonia or dust in the air of the housing facilities.
Burn empty bottles, caps and all unused vaccine and accessories.
Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons, if this is suspected, seek veterinary advice and notify the registration holder. 

Precautions:
Avoid contact with eyes, hands and clothing when handling/administering the vaccine.
Do not dilute the vaccine or otherwise stretch the dosage.
Do not spill or spatter the vaccine.
Use entire contents of each vial when first opened.
Wash hands after vaccination.

Contraindications:
The application of Newcastle Disease or Bronchitis vaccine, either singly or in combination should be avoided for a three day period prior to and for three days after the application of LT-IVAX ASL.

Directions for Use:  Use only as directed.
In outbreak situations, vaccinate healthy fowls first, progressing toward outbreak areas in order to vaccinate diseased fowls last.

Vaccinate by the EYEDROP METHOD according to the following schedule:

• When to vaccinate.
  Initial vaccination Revaccination
  4 weeks of age 10 weeks of age or older

• Vaccination programme.
  • The development of a durable strong protection depends upon the use of an effective vaccination program as well as many circumstances such as administration techniques, environment and flock health at time of vaccination. 
  • Although disease may not be evident, coccidiosis, chronic respiratory disease, mycoplasma infection, lymphoid leucosis, infectious bursal disease, Marek’s disease, or other disease conditions may cause serious complications or reduce protection.
  • The immune response to one vaccination under field conditions is seldom complete for all fowls within a given flock. Even when vaccination is successful, the protection stimulated in individual fowls against different diseases may not be life long.
  • If necessary, the vaccine may be used to aid in limiting the spread of an outbreak; however, only fowls not yet infected with the virulent outbreak virus can be protected.
  • Examination of fowls for vaccination “takes” is unnecessary and so-called “takes” are not to be expected.
  • As with all live virus vaccines, a mild transitory reaction may occur in a small portion of the flock, and with LT-IVAX ASL, this is generally limited to a mild, localized eye reaction of short duration.
    
• Preparation of the vaccine
  • Do not open and mix the vaccine until ready for use. 
  • Mix only one vial at a time and use entire contents within 2 hours.
  • Remove the tear- off aluminium seal and stopper from vial containing the dried vaccine.
  • Remove the tear- off aluminium seal and stopper from the bottle containing the diluent and insert the long end of the adapter into the diluent bottle.
  • Hold the diluent bottle firmly in an upright position and insert the vaccine vial on the adapter of the diluent bottle. The neck of the vaccine vial should snap into position and should be seated securely on the adapter on the diluent bottle.
  • Invert the two containers so that the vaccine vial is on the bottom and allow the diluent to flow into the vaccine vial. If the diluent does not flow freely, squeeze the diluent bottle gently and the diluent will flow into the vaccine vial. The vaccine vial should be completely filled with diluent to prevent excess foaming.
  • Hold the joined containers by the ends; shake vigorously until the vaccine plug is completely dissolved.
  • Return the joined containers to its original position (diluent bottle on the bottom).
  • Allow the vaccine to flow into the diluent bottle. If the vaccine does not flow into the diluent bottle, tap or squeeze the diluent bottle gently and release to draw the vaccine into the diluent bottle. Ensure that all the product is removed from the vaccine vial.
  • Remove the vaccine vial and adapter from the neck of the diluent bottle and insert dropper applicator into plastic diluent bottle.
  • The vaccine is now ready for use.
  • Wash hands thoroughly after mixing the vaccine.
    
• How to vaccinate
  • Hold dropper bottle in vertical position throughout vaccination to avoid wasting vaccine.
  • Instil one full drop of rehydrated vaccine into the open eye of the fowl and hold until a swallowing motion is observed.

Presentation
500 or 1000  dose vials with diluent (15 or 30mℓ)

Registration holders:

Schering-Plough Animal Health
Co. Reg. No. 1934/005207/07