FOR ANIMAL USE ONLY
Reg. No. G2707 (Act 36/1947)
Namibia Reg. No. V05/24.3/658 NS0
Newcastle disease is a notifiable disease in terms of the Animal Diseases Act (Act35/1984). The occurrence of suspicion of this disease has to be reported to the responsible state Veterinarian.
Nobilis® G+ND is a combined inactivated vaccine for primed chickens and is recommended for the protection of the progeny of breeders against Infectious Bursal Disease (Gumboro) during the first weeks of their life and for the booster vaccination of future breeders and layers against Newcastle Disease.
Each 0,5 mℓ dose of Nobilis® G+ND contains Infectious Bursal Disease (Gumboro) inducing ≥14,5 log2 VN units and Newcastle Disease virus Clone 30 ≥50 PD50. The viruses were grown in embryonated eggs or Vero Cell cultures and were inactivated with formalin and subsequently suspended in the aqueous phase of an oil adjuvant emulsion.
- Store in the dark between 2 °C and 8 °C.
- Do not freeze.
- Avoid prolonged or repetitive exposure to high ambient temperatures following withdrawal from the refrigerator prior to use.
- Protect from exposure to direct sunlight.
- Withdrawal period: Do not market chickens for slaughter purposes for at least 6 weeks after vaccination.
- Avoid intravenous injection.
- Vaccinate healthy chickens only.
- Ensure that chickens marketed do not have swellings at the site of vaccine administration, as this may result in the condemnation of the chickens.
- Vaccination of chickens in production may lead to a slight decrease in egg production.
- Accidental self-vaccination may lead to severe local allergic reaction. Consult a physician informing him/her that the vaccine contains a mineral oil.
- Opened bottle should be used within 3 hours.
- Do not store partially used vaccine containers for future use and use the entire contents once opened.
- Destroy any unused vaccine as well as all vaccine containers and vaccination equipment according to local waste disposal regulations.
- KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
- Although this vaccine has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.
- Do not mix Nobilis® G+ND with other vaccines.
- Observe aseptic precautions. Ensure that all vaccination equipment (needles, syringes, etc.) are clean and sterile prior to and during use.
- It is essential to adhere to the vaccination programme to maintain a satisfactory immune status.
- It is good vaccination practice when handling the vaccine to avoid contact with the eyes, hands and clothing.
DIRECTIONS FOR USE – USE ONLY AS DIRECTED
Shake well before use and at regular intervals during the vaccination process.
Recommended vaccination programme
Nobilis® G+ND should be given to chickens around 16 to 20 weeks of age, but not less than 4 weeks before the onset of lay.
For an optimal booster effect, the chickens must be primed with a live vaccine against Newcastle Disease and Infectious Bursal Disease.
The best results will be obtained if vaccination with inactivated vaccine takes place 6 or more weeks after administration of the live primer, but under no circumstances should it be done earlier than 4 weeks after priming.
Dosage and Administration
- Each chicken should be given 0,5 mℓ of the vaccine intramuscularly into the thigh or breast muscle or subcutaneously into the back of the neck. (Administration via intramuscular injection into the breast muscle, the needle should be pointed in the direction of the chicken’s head, to prevent the needle from entering the body cavity.)
- Allow the vaccine to gradually reach room temperature (20 °C to 25 °C) prior to use.
- Shake well before use and at regular intervals during the vaccination process.
- Remove the aluminium overseal and the vaccine is ready for use.
- Inject all the chickens in the flock.
If priming and subsequent vaccination have been carried out correctly the chickens will develop antibodies at a level which provides protection against Newcastle Disease.
Under normal field situations, the offspring hatched at any stage of the laying period will have sufficient maternal antibodies to protect them against Infectious Bursal disease (Gumboro) infections during the first week of life.
In healthy chickens, no clinical reaction to the vaccination will be observed. For some weeks after vaccination, a slight swelling may be felt at the site of the vaccination. This does not constitute permanent damage of the tissue provided that the vaccination has been carried out aseptically.
Bottles containing 500 mℓ sufficient for 1 000 doses packed in a cardboard box.
REGISTRATION HOLDER MANUFACTURER
Intervet South Africa (Pty) Ltd. Intervet International B.V.
20 Spartan Road, Spartan 35 Wim de Körverstraat
1619, RSA Boxmeer, The Netherlands
Tel: +27 (0) 11 923 9300
Fax: +27 (0) 11 392 3158
DATE OF PUBLICATION OF THIS PACKAGE INSERT
3 December 2014