Product Details - COVEXIN® 10

CattleSheep

Product Class

COVEXIN 10

COVEXIN 10

Reg. No. G3354 (Act 36/1947)

Namibia Reg. No. V05/24.4/413 NS0

 

Clostridial vaccine for sheep and cattle.

 

INDICATIONS

For the active immunisation of sheep and cattle from 2 weeks of age to prevent mortality, lesions and clinical signs of disease caused by Clostridium perfringens type A (enterotoxemia, haemorrhagic enteritis), C. perfringens type B (lamb dysentery), C. perfringens type C (necrotic enteritis), C. perfringens type D (enterotoxemia/pulpy kidney), C. chauvoei (blackleg/black quarter), C. novyi type B (infectious necrotic hepatitis), C. septicum (malignant oedema), C. tetani (tetanus), C. sordellii (sudden death syndrome/haemorrhagic enteritis) and C. haemolyticum (bacillary haemoglobinuria).

Immunity is established within 14 days of administration of the second dose and lasts for 1 year.

 

COMPOSITION

 

POTENCY VALUE/DOSE

C. perfringens type A toxoid

≥ 0,5 IU

C. perfringens type B toxoid

≥ 10 IU β/≥ 5 IU ٤

C. perfringens type C toxoid

≥ 10 IU β

C. perfringens type D toxoid

≥ 5 IU ٤

C. chauvoei whole culture

Meets Ph. Eur.

C. novyi toxoid

≥ 3,5 IU

C. septicum toxoid

≥ 2,5 IU

C. tetani toxoid

≥ 2,5 IU

C. sordellii toxoid

≥ 1,0 U

C. haemolyticum toxoid

≥ 10 U

 

STORAGE

  • Store between 2 ºC and 8 ºC.
  • Do not freeze.
  • Protect from light.
  • Opened bottles should be discarded within 8 hours of opening.

 

WARNINGS

  • Withdrawal period: Do not slaughter animals for human consumption within 21 days* of vaccination.
  • Vaccinate healthy animals only.
  • It is not recommended that other vaccines be administered within 14 days before or after vaccination with this product.
  • Only sterile syringes and needles should be used. The injection should be made through an area of clean, dry skin.
  • Partially used containers and vaccination equipment should be discarded according to local waste disposal regulations at the end of the day's operations, as under field conditions it may be difficult to avoid accidental contamination.
  • Cattle: Swelling may occur at the site of injection which should resolve within 1 to 2 months. The incidence and severity may be higher in calves less than 1 month of age.
  • Sheep: Swelling may occur at the site of injection which should resolve within 1 to 2 months post-vaccination.
  • As with any vaccine occasional hypersensitivity reactions may occur. In such cases consult your veterinarian.
  • KEEP OUT OF REACH OF CHILDREN, UNINFORMED PERSONS AND ANIMALS.
  • Although this vaccine has been tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

* 21 days is a standard withdrawal period set according to South African legislation for all vaccine products. If required by national legislation another withdrawal period may also be licensed, e.g. 0 days.

DIRECTIONS FOR USE - USE ONLY AS DIRECTED

Shake well before and during use.

 

Administration

Subcutaneous injection, preferably in the loose skin on the side of the neck.

 

Dosage

  • Sheep and lambs over 2 weeks of age
    Two injections of 1 mℓ each at an interval of 6 weeks, and a booster annually thereafter.
    The vaccine course should be completed at least 2 weeks before maximum immunity is required i.e. a period of risk, or in pregnant ewes during lambing.
    Previously sensitised ewes should be injected 2 to 6 weeks before lambing is due to commence. This provides passive protection of the lamb, via the colostrum, for up to 12 weeks.
    The vaccine may be used in lambs as young as 2 weeks of age regardless of serum antitoxin levels acquired from maternal transfer.
  • Cows and calves over 2 weeks of age
    Two injections of 2 mℓ each at an interval of 6 weeks, and a booster annually thereafter.
    Previously sensitised cows should be injected 2 to 6 weeks before calving is due to commence. This provides passive protection of the calf, via the colostrum, for up to 12 weeks. The vaccine may be used in calves as young as 2 weeks of age regardless of serum antitoxin levels acquired from maternal transfer.

 

REGISTRATION HOLDER

Cooper Veterinary Products (Pty) Ltd.

Private Box X2026

Isando, 1600, RSA

Tel: +27 (0) 11 923 9300

 

MARKETED BY

MSD Animal Health

20 Spartan Road, Spartan

1619, RSA

Tel: +27 (0) 11 923 9300

Fax: +27 (0) 11 392 3158

www.msd-animal-health.co.za

 

DATE OF PUBLICATION OF PACKAGE INSERT

30 October 2003