PARACOX®-5

Poultry

Product Details - PARACOX®-5



Reg. No. G2817 Act 36/1947


For use by or under the control of a veterinarian only.

ATTENUATED ORAL COCCIDIOSIS VACCINE FOR FOWLS

Claims:

For the active immunisation of broilers against Eimeria acervulina, E. maxima, E. mitis and E. tenella.

Presentation:

Paracox-5 is a translucent, aqueous suspension of oocysts derived from five precocious lines of coccidia, presented as a live, attenuated oral vaccine.

Storage:

Store in a refrigerator at a temperature between 2°Cand 8°C.

Do not store below 2°C.

DO NOT FREEZE.

Protect from light.

Empty and partially used vials should be incinerated.

Composition:

Each 0,004 mℓ dose of vaccine contains the following numbers of sporulated oocysts derived from precocious lines of coccidia:

E. acervulina HP 500 -650

E. maxima CP 200 - 230

E. maxima MFP 100 - 130

E. mitis HP 1 000 - 1 300

E. tenella HP 500 - 650

Warnings:

TO BE USED FOR THE IMMUNISATION OF BROILERS ONLY.

Withdrawal period: nil.

Vaccinate healthy fowls only.

Keep out of reach of children, uninformed persons and pets.

Freezing this vaccine will inactivate it, do not under any circumstances use this vaccine if it has been frozen.

Food and water provided at any stage before or after vaccination must be free from anticoccidial agents including sulphonamides and antibacterial agents having anticoccidial activity (viz. oxytetracycline, chlortetracycline, furazolidone, nitrofurazone).

For oral use only.

The vaccine will not actively immunise avian species other than the fowl against coccidiosis nor will it confer immunity against Eimeria spp. other than those contained in the vaccine.

Although this vaccine has been extensively tested under a wide variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected notify your veterinarian or the registration holder.

Precautions:

Since immunity to coccidial infection following Paracox-5 administration is enhanced by natural challenge, it should be noted that access to any agents having anticoccidial activity at any time following vaccination may reduce the duration of effective immunity.

To reduce the chances of coccidial field challenge occurring before the full development of immunity, housing should be thoroughly cleaned between rearing cycles.

Partially used containers and diluted vaccine must be discarded immediately following one vaccination

session, as under field conditions it may be difficult to avoid accidental contamination of the vaccine.

Use before expiry date on carton.

Directions for Use: Use only as directed

A single dose of Paracox-5 should be administered to chicks in one of the following ways:

1.In the hatchery spray.

2.From one-day-old via feed.

The minimum dose of vaccine is 0,004 mℓ per chick. Each 4 mℓ vial will provide sufficient vaccine for 1000 chicks, and each 20 mℓ vial will provide sufficient vaccine for 5 000 chicks.

By hatchery spray
Determine the delivery capacity of the Spraycox cabinet or the spray cabinet as recommended by Schering-Plough, in terms of the volume delivered per 100 chicks.

Dilution of 5 000 dose vial:

Multiply the delivery capacity (per 100 chicks) by 50 to give the total volume of diluted vaccine required for 5 000 doses and add this volume of water to a suitable container (normally between 1.0 and 1.5 litres for 5 000 doses).

Delivery Capacity of Spray Cabinet (mℓ) per 100 chicks x 50 (containers of 100 chicks each) = Volume of water (mℓ) needed to dilute 1 x 5 000 dose vial.

Dilution of 1 000 dose vial:

Multiply the delivery capacity (per 100 chicks) by 10 to give the total volume of diluted vaccine required for 1 000 doses and add this volume of water to a suitable container (normally between 200 and 300mℓ for 1 000 doses).

Delivery Capacity of Spray Cabinet (mℓ) per 100 chicks x 10 (containers of 100 chicks each) = Volume of water (mℓ) needed to dilute 1 x 1 000 dose vial

Add sufficient red food colourant (such as Cochineal Red) to the water to give a concentration of 0,1% w/v.

Shake one 5 000 dose (or 1 000 dose) vial of Paracox-5 vigorously for 30 seconds to ensure re-suspension of the oocysts. Add the entire contents of the vial to the diluent and mix thoroughly. Add the diluted vaccine to the applicator reservoir and operate the cabinet to spray evenly over the chicks using a coarse spray.

Ensure a controlled even coverage of the total internal surface area of the box containing the chicks. Agitate the applicator reservoir regularly throughout application to avoid settling out of oocysts. Vaccine should be delivered using a dose volume of between 0.21 and 0.28 mℓ per chick.

Prepare chicks for delivery to rearing accommodation.

Administration via feed

Sufficient starter feed for the first 24-48 hours should be laid out on paper or plastic along the floor of the poultry house.

Shake the vial vigorously for 30 seconds before use, to ensure re-suspension of the oocysts.

Dilute Paracox-5 in water at the rate of approximately 5 000 doses in up to 3 litres of water and spray evenly over the surface of the feed using a coarse spray. Ensure a controlled, even coverage of the total surface area of the feed available to the chicks.

Agitate the applicator reservoir regularly throughout application to prevent oocysts from settling out.

Ensure that all available feed is treated and that the total number of doses dispensed matches the number of fowls in the house.

Vaccine may be sprayed on the feed from placement onwards.

When treated allocation of feed has been consumed, routine feeding may continue.

Presentation:

4 mℓ (1 000 doses) / 20 mℓ (5 000 doses)

Registration holder:

Schering-Plough Animal Health
Co. Reg. No. 1934/005207/07