Product Details - MASTICILLIN DC

Indication
For routine use in cows at drying off, to treat existing intramammary infections and to assist in preventing new infections occurring during the dry period. Masticillin DC contains cloxacillin, which is active against the following major pathogens associated with mastitis: penicillin resistant and sensitive Staphylococcus aureus, Arcanobacterium (Corynebacterium) pyogenes, Streptococcus spp. including S. agalactiae and S. uberus.

Storage Instruction
Store in a cool place, below 25 ºC.

Composition
Each single dose syringe contains 500 mg Cloxacillin in the benzathine form.

Pharmacological action
Cloxacillin, a semi-synthetic penicillin resistant to staphylococcal penicillinase, is especially used for dry cow intramammary infusions. Cloxacillin has a bactericidal action on a wide range of organisms implicated in chronic mastitis. The less soluble benzathine salt of cloxacillin in a base containing 3 % aluminium monostearate in mineral oil provides therapeutic levels of cloxacillin in the udder for 3 to 4 weeks during the dry period.

Warnings

• Do not treat cows during lactation.
• Milk from treated animals must not be used for human consumption, industrial purposes or mixed with bulk milk within 28 days after treatment plus 120 hours (10 milkings) after calving.
• Masticillin DC is not intended for use within 28 days of calving.
• Animals intended for human consumption should not be slaughtered until 28 days after the last treatment.
• Keep out of reach of children and uninformed persons.
• Although this remedy has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and inform the registration holder.

Direction for Use:  USE ONLY AS DIRECTED - For intramammary administration only

• Before infusion, the teats should be thoroughly cleaned and disinfected and care should be taken to avoid contamination of the injector nozzle.
• Administer the contents of one full syringe into each quarter after the last milking on the day of drying off.
• Ensure that this process is carried out as aseptically as possible.
• Each syringe must only be used once. Partly used syringes must be discarded.

Presentation & Identification
Each 3 g single dose syringe contains an off-white suspension. Each shipper contains 24 x 3 g syringes or 20 x 3 g syringes.

Registration Holder:
Intervet SA (Pty) Ltd
Reg. No. 1991/006580/07